A gorilla, a crocodile, and a wolf fall victim to evil genetic experiments. In the course of these changes, DNA changes make them total; become unusually strong, fast, bulky but also extremely aggressive. Johnson plays the role of Davis Okoye, a lone primate specialist, who develops a close friendship with the gorilla, an unusual occurrence, touched by a sort of albinism, George. Together with a disregarded geneticist, the hero struggles to get the antidote that will save his friend.

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