Emily (Rooney Mara) and Martin (Channing Tatum) form an enviable couple who lead a luxurious and carefree life until he is arrested for fraud and sentenced to four years in prison. After his sentence, Martin is greeted by a wife totally changed, at the lowest levels of depression and suicidal. Thus, Emily reaches psychiatrist (Jude Law), who recommended treatment found in an experimental phase. When side effects do apparently to kill her husband, her psychiatrist tries to find out if this is really accidental murder or a well tuned.
Directed by Steven Soderbergh, adverse effects is an unpredictable psychological thriller with Jude Law, Rooney Mara, Catherine Zeta-Jones and Channing Tatum starring.